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id="inside_rnewtil">水系統(tǒng)污染、濾膜生物膜增長(zhǎng)，如何正確清潔滅菌?奧克泰士給答案?。。?/h1> <div id="z5vmetedr" class="inside_rnewtime">更新時(shí)間：2025-06-27 點(diǎn)擊次數(shù)：66次</div> <div id="z5vmetedr" class="inside_rnewcon"><section style="line-height: 1.6; box-sizing: border-box; text-align: justify; font-size: 16px;"><section style="color: rgb(62, 62, 62); text-align: center; font-size: 28px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">水系統(tǒng)污染、濾膜生物膜增長(zhǎng)，如何正確清潔滅菌?奧克泰士給答案?。?！</p></section><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br/></p><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p><section style="color: rgb(62, 62, 62); margin-top: 10px; margin-bottom: 10px; position: static; box-sizing: border-box;"><section style="padding: 0.5em; border: 0.1em solid rgb(128, 128, 128); border-radius: 15px; box-sizing: border-box;"><section style="border-color: black; border-width: 3px; padding: 10px; border-radius: 15px; border-style: solid; box-sizing: border-box;"><section style="text-align: center; font-size: 17px; box-sizing: border-box;"><p style="text-align: justify; margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="color: rgb(0, 0, 0); box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">引言：</span></strong></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br/></p><p style="text-align: justify; margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="box-sizing: border-box;"> 潔凈區(qū)作為制藥、醫(yī)療器械、食品等高風(fēng)險(xiǎn)行業(yè)的核心公用系統(tǒng)，其環(huán)境控制直接關(guān)系到產(chǎn)品質(zhì)量與患者安全。<strong style="box-sizing: border-box;">在實(shí)際生產(chǎn)中，潔凈區(qū)因設(shè)備維護(hù)、季節(jié)性停產(chǎn)、工藝調(diào)整等原因需周期性停用并重啟的情況普遍存在。</strong>據(jù)統(tǒng)計(jì)，國(guó)內(nèi)制藥企業(yè)年均潔凈區(qū)停用量達(dá)20%以上，<strong style="box-sizing: border-box;"><span style="color: rgb(255, 129, 36); box-sizing: border-box;">而重啟后因清潔滅菌不規(guī)范導(dǎo)致的微生物污染事件占環(huán)境偏差的35%。</span></strong>如何在停用期間維持潔凈區(qū)的環(huán)境穩(wěn)定性，并在重啟時(shí)快速恢復(fù)合規(guī)狀態(tài)，已成為行業(yè)關(guān)注的焦點(diǎn)。</span></p><p style="text-align: justify; margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p><section style="color: rgb(160, 160, 160); font-size: 14px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"> 關(guān)鍵詞：消毒劑、殺孢子劑、水系統(tǒng)、注射用水系統(tǒng)、純化水、注射用水、濾膜清洗、超濾膜、滲透膜、二級(jí)反滲透膜、微生物、微生物污染、BCC、洋蔥伯克霍爾德菌、公用系統(tǒng)重啟、季節(jié)性停產(chǎn)、停產(chǎn)重啟、停機(jī)、水系統(tǒng)管理處理、無(wú)菌處理、無(wú)菌體系、無(wú)菌環(huán)境、無(wú)菌參數(shù)、環(huán)境監(jiān)測(cè)、環(huán)境數(shù)據(jù)統(tǒng)計(jì)。</p></section><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p><section style="color: rgb(62, 62, 62); text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; background-color: rgb(149, 185, 238); min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; padding: 0px 10px; box-sizing: border-box;"><section style="text-align: center; margin: 6px 0px 0px; position: static; box-sizing: border-box;"><section style="color: rgb(255, 255, 255); font-size: 20px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">一、水系統(tǒng)處理技術(shù)體系構(gòu)建</strong></p></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; margin: 0px 0px 0px -1px; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; background-image: linear-gradient(90deg, rgba(235, 246, 255, 0) 0%, rgb(235, 246, 255) 80%); box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: middle; width: auto; align-self: center; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="margin: 0.5em 0px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section><section style="display: inline-block; vertical-align: middle; width: auto; flex: 0 0 0%; height: auto; align-self: center; box-sizing: border-box;"><section style="text-align: right; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 0px; height: 0px; vertical-align: top; overflow: hidden; border-style: solid; border-width: 19px 12px 19px 0px; border-color: rgba(255, 255, 255, 0) rgb(149, 185, 238) rgba(255, 255, 255, 0) rgba(255, 255, 255, 0); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section></section></section></section></section></section></section><section style="color: rgb(62, 62, 62); text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: auto; vertical-align: top; align-self: flex-start; flex: 100 100 0%; border-style: solid; border-width: 0px 0px 0px 1px; border-color: rgb(195, 224, 247); height: auto; margin: 0px 0px 0px 4px; box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; padding: 0px 27px; box-sizing: border-box;"><section style="text-align: justify; font-size: 17px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（一）水質(zhì)標(biāo)準(zhǔn)與系統(tǒng)分類</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">水系統(tǒng)根據(jù)用</span><span style="font-size: 18px; box-sizing: border-box;">途分為三類： </span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 129, 36); box-sizing: border-box;">1. 純化水（PW）：</span><span style="font-size: 18px; box-sizing: border-box;">電導(dǎo)率≤5.1μS/cm，用于設(shè)備清洗、配料等，需控制微生物≤100CFU/ML；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 129, 36); box-sizing: border-box;">2. 注射用水（WFI）：</span><span style="font-size: 18px; box-sizing: border-box;">內(nèi)毒素≤0.25EU/ML，采用70℃以上循環(huán)輸送，用于注射劑配制；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 129, 36); box-sizing: border-box;">3. 滅菌注射用水：</span><span style="font-size: 18px; box-sizing: border-box;">通過(guò)終端滅菌（如121℃/15分鐘）制備，作為溶媒或稀釋劑。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（二）預(yù)處理單元：污染物攔截的第一道防線</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">1.原水凈化技術(shù)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 多介質(zhì)過(guò)濾：填充石英砂、活性炭，去除懸浮物（濁度≤1NTU）及余氯（≤0.1ppm）；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 軟化處理：離子交換樹(shù)脂去除鈣鎂離子，防止RO膜結(jié)垢（特別注意結(jié)垢需要對(duì)第一層、第二層反滲透膜均進(jìn)行清洗且不可同時(shí)清洗）；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 精密過(guò)濾：5μm濾芯截留顆粒雜質(zhì)，保護(hù)后續(xù)膜元件。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">2.2025 GMP新增要求</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 活性炭過(guò)濾器需設(shè)置微生物監(jiān)控點(diǎn)，每周（實(shí)際生產(chǎn)周期）檢測(cè)TOC（≤0.5mg/L），避免活性炭成為生物膜滋生地；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 預(yù)處理管道需采用316L不銹鋼電拋光材質(zhì)，死角長(zhǎng)度L≤3D（D為管道直徑）。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（三）核心處理：膜技術(shù)的精準(zhǔn)應(yīng)用</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（1）反滲透（RO）系統(tǒng)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 技術(shù)參數(shù)：脫鹽率≥99.5%，回收率控制在75%以下<strong style="box-sizing: border-box;">（避免濃水側(cè)結(jié)垢）</strong>，運(yùn)行流速≥1.2m/s<strong style="box-sizing: border-box;"><span style="color: rgb(255, 0, 0); box-sizing: border-box;">（湍流狀態(tài)下可以有效抑制生物膜粘滯，減少泛濫風(fēng)險(xiǎn)）</span></strong>；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 節(jié)能升級(jí)：采用低壓大通量膜元件，配合變頻泵動(dòng)態(tài)調(diào)節(jié)壓力，降低能耗。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（2）電去離子（EDI）系統(tǒng)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 深度除鹽：替代傳統(tǒng)混床，產(chǎn)水電導(dǎo)率≤0.1μS/cm，無(wú)需酸堿再生，符合環(huán)保要求；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 微生物控制：<span style="color: rgb(255, 129, 36); box-sizing: border-box;">定期用<strong style="box-sizing: border-box;"><span style="color: rgb(255, 0, 0); box-sizing: border-box;">奧克泰士消毒劑</span></strong>循環(huán)消毒（良好周期內(nèi)），防止EDI模塊內(nèi)部生物膜形成。</span></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（四）后處理與分配系統(tǒng)：水質(zhì)維持的關(guān)鍵</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">1.消毒滅菌技術(shù)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 化學(xué)藥劑消毒：采用<span style="color: rgb(255, 0, 0); box-sizing: border-box;">奧克泰士消毒劑</span>按照一定配比加入，進(jìn)行循環(huán)消毒，滿足水系統(tǒng)標(biāo)準(zhǔn)及內(nèi)控符合實(shí)際生產(chǎn)SOP，確保達(dá)到要求標(biāo)準(zhǔn)。</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 巴氏滅菌：<span style="color: rgb(255, 129, 36); box-sizing: border-box;">純化水系統(tǒng)80℃循環(huán)1小時(shí)，注射用水系統(tǒng)75℃以上持續(xù)循環(huán)，每季度驗(yàn)證升溫速率（≥1℃/分鐘）；</span></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 臭氧消毒：濃度0.3-0.5mg/L，接觸時(shí)間≥30分鐘，消毒后需通過(guò)活性炭吸附去除殘留（臭氧≤0.01mg/L）。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">2.儲(chǔ)罐與管道設(shè)計(jì)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 儲(chǔ)罐頂部安裝疏水性除菌濾器（0.22μm PVDF材質(zhì)），呼吸口設(shè)置防蟲(chóng)網(wǎng)；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 分配管道采用3D全焊式連接，焊接缺陷率≤0.1%（通過(guò)內(nèi)窺鏡檢測(cè)），流速≥2.0m/s<span style="color: rgb(255, 0, 0); box-sizing: border-box;">（注射用水系統(tǒng)，湍流狀態(tài)減少生物膜粘滯）。</span></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section><section style="justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: bottom; width: auto; line-height: 0; align-self: flex-end; flex: 0 0 0%; height: auto; box-sizing: border-box;"><section style=" transform: translate3d(-5px, 0px, 0px); -webkit-transform: translate3d(-5px, 0px, 0px); -moz-transform: translate3d(-5px, 0px, 0px); -o-transform: translate3d(-5px, 0px, 0px); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 9px; height: 9px; vertical-align: top; overflow: hidden; border-radius: 100px; background-color: rgb(195, 224, 247); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section><section style="display: inline-block; vertical-align: bottom; width: auto; flex: 100 100 0%; height: auto; align-self: flex-end; padding: 0px; box-sizing: border-box;"><section style="color: rgb(195, 224, 247); box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">Oxytech<br style="box-sizing: border-box;"/></p></section><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style=" transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); text-align: center; margin: 0px 0px 3px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section></section></section></section></section><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p><section style="color: rgb(62, 62, 62); text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; background-color: rgb(149, 185, 238); min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; padding: 0px 10px; box-sizing: border-box;"><section style="text-align: center; margin: 6px 0px 0px; position: static; box-sizing: border-box;"><section style="text-align: justify; color: rgb(255, 255, 255); font-size: 20px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">二、濾膜清潔核心技術(shù)：從污染診斷到工藝實(shí)施</strong></p></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; margin: 0px 0px 0px -1px; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; background-image: linear-gradient(90deg, rgba(235, 246, 255, 0) 0%, rgb(235, 246, 255) 80%); box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: middle; width: auto; align-self: center; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="margin: 0.5em 0px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section><section style="display: inline-block; vertical-align: middle; width: auto; flex: 0 0 0%; height: auto; align-self: center; box-sizing: border-box;"><section style="text-align: right; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 0px; height: 0px; vertical-align: top; overflow: hidden; border-style: solid; border-width: 19px 12px 19px 0px; border-color: rgba(255, 255, 255, 0) rgb(149, 185, 238) rgba(255, 255, 255, 0) rgba(255, 255, 255, 0); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section></section></section></section></section></section></section><section style="color: rgb(62, 62, 62); text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: auto; vertical-align: top; align-self: flex-start; flex: 100 100 0%; border-style: solid; border-width: 0px 0px 0px 1px; border-color: rgb(195, 224, 247); height: auto; margin: 0px 0px 0px 4px; box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; padding: 0px 27px; box-sizing: border-box;"><section style="text-align: justify; font-size: 17px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">1. 濾膜污染類型與診斷方法</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（1）診斷技術(shù)升級(jí)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 在線監(jiān)測(cè)：集成電導(dǎo)率、TOC、壓差（ΔP）傳感器，當(dāng)ΔP上升≥15%或產(chǎn)水量下降≥20%時(shí)觸發(fā)清洗；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 離線檢測(cè)：膜元件抽樣培養(yǎng)，鑒定優(yōu)勢(shì)菌屬（如洋蔥伯克霍爾德菌）。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">2. 不同類型濾膜的清潔工藝</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（1）反滲透（RO）膜：生物膜防控的核心戰(zhàn)場(chǎng)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 129, 36); box-sizing: border-box;">輕度污染（生物膜初期）</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 129, 36); box-sizing: border-box;">- 物理清洗：35℃純化水高流速?zèng)_洗，配合氣水脈沖氣；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 129, 36); box-sizing: border-box;">- 化學(xué)清洗：0.5%過(guò)氧乙酸溶液循環(huán)60分鐘，浸泡30分鐘（殺滅細(xì)菌及孢子），沖洗至余氧≤0.1ppm。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 0, 0); box-sizing: border-box;">重度污染（生物膜成熟期）</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 0, 0); box-sizing: border-box;">- 復(fù)合清洗劑：利用<strong style="box-sizing: border-box;">奧克泰士消毒劑</strong>分解胞外聚合物（EPS）；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 0, 0); box-sizing: border-box;">- 還原處理：若使用次氯酸鈉，需用1%亞硫酸氫鈉中和，避免膜氧化損傷。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（2）超濾膜（UF）：大分子污染物的定向清除</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 在線反沖洗：每運(yùn)行4小時(shí)用產(chǎn)水反向沖洗（壓力0.15MPa，時(shí)間60秒，以內(nèi)部慣用標(biāo)準(zhǔn)為主），通量恢復(fù)率≥95%；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 化學(xué)強(qiáng)化清洗：蛋白質(zhì)污染用1%胰蛋白酶溶液（pH 8.5，37℃）循環(huán)2小時(shí)，油脂污染用2%碳酸鈉溶液（40℃）浸泡。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（3）微孔濾膜（除菌級(jí)）：低損傷清潔策略</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="color: rgb(255, 129, 36); font-size: 18px; box-sizing: border-box;"><strong style="box-sizing: border-box;">- 材質(zhì)禁忌：禁用強(qiáng)酸強(qiáng)堿，僅用注射用水或奧克泰士產(chǎn)品沖洗（避免膜孔堵塞）；</strong></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 完整性測(cè)試：每次使用前后進(jìn)行泡點(diǎn)測(cè)試（乙醇浸潤(rùn)法，泡點(diǎn)壓力≥3.2bar），確保0.22μm孔徑無(wú)缺陷。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">3. 清洗劑選擇與安全控制</span></strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（1）核心原則</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; color: rgb(255, 0, 0); box-sizing: border-box;">- 兼容性優(yōu)先：聚酰胺RO膜禁用游離氯（≤0.1ppm），PVDF超濾膜可耐受奧克泰士產(chǎn)品；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 效率與殘留平衡：酶清洗劑需控制殘留（蛋白質(zhì)檢測(cè)≤0.1μg/ML），化學(xué)消毒劑需沖洗至TOC≤0.5mg/L。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">（2）新型環(huán)保清洗劑</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 復(fù)合型銀離子消毒劑：奧克泰士殺孢子劑，兼具氧化與剝離作用，無(wú)有害殘留，符合FDA清潔驗(yàn)證要求；</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 生物降解型表面活性劑：如烷基糖苷（APG），可替代傳統(tǒng)SDS，減少?gòu)U水處理負(fù)荷。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section><section style="justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: bottom; width: auto; line-height: 0; align-self: flex-end; flex: 0 0 0%; height: auto; box-sizing: border-box;"><section style=" transform: translate3d(-5px, 0px, 0px); -webkit-transform: translate3d(-5px, 0px, 0px); -moz-transform: translate3d(-5px, 0px, 0px); -o-transform: translate3d(-5px, 0px, 0px); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 9px; height: 9px; vertical-align: top; overflow: hidden; border-radius: 100px; background-color: rgb(195, 224, 247); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section><section style="display: inline-block; vertical-align: bottom; width: auto; flex: 100 100 0%; height: auto; align-self: flex-end; padding: 0px; box-sizing: border-box;"><section style="color: rgb(195, 224, 247); box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">Oxytech<br style="box-sizing: border-box;"/></p></section><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style=" transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); text-align: center; margin: 0px 0px 3px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section></section></section></section></section><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p><section style="color: rgb(62, 62, 62); text-align: center; margin-top: 10px; margin-bottom: 10px; line-height: 0; position: static; box-sizing: border-box;"><section style="max-width: 100%; vertical-align: middle; display: inline-block; line-height: 0; box-sizing: border-box;"></section></section><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p><section style="color: rgb(62, 62, 62); text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; background-color: rgb(149, 185, 238); min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; padding: 0px 10px; box-sizing: border-box;"><section style="text-align: center; margin: 6px 0px 0px; position: static; box-sizing: border-box;"><section style="text-align: justify; color: rgb(255, 255, 255); font-size: 20px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">三、污染防控與合規(guī)管理：從源頭到驗(yàn)證的全鏈條把控</strong></p></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; margin: 0px 0px 0px -1px; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; background-image: linear-gradient(90deg, rgba(235, 246, 255, 0) 0%, rgb(235, 246, 255) 80%); box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: middle; width: auto; align-self: center; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="margin: 0.5em 0px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section><section style="display: inline-block; vertical-align: middle; width: auto; flex: 0 0 0%; height: auto; align-self: center; box-sizing: border-box;"><section style="text-align: right; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 0px; height: 0px; vertical-align: top; overflow: hidden; border-style: solid; border-width: 19px 12px 19px 0px; border-color: rgba(255, 255, 255, 0) rgb(149, 185, 238) rgba(255, 255, 255, 0) rgba(255, 255, 255, 0); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section></section></section></section></section></section></section><section style="color: rgb(62, 62, 62); text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: auto; vertical-align: top; align-self: flex-start; flex: 100 100 0%; border-style: solid; border-width: 0px 0px 0px 1px; border-color: rgb(195, 224, 247); height: auto; margin: 0px 0px 0px 4px; box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; padding: 0px 27px; box-sizing: border-box;"><section style="text-align: justify; font-size: 17px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">1. 系統(tǒng)設(shè)計(jì)階段的前瞻性防控</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 管道布局：采用建模優(yōu)化流道，消除盲管、死角，焊接接口進(jìn)行內(nèi)窺鏡檢測(cè)（每100個(gè)焊口抽檢5個(gè)，通常內(nèi)部標(biāo)準(zhǔn)為15個(gè)）；</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 材質(zhì)升級(jí)：RO膜殼選用內(nèi)襯聚四氟乙烯（PTFE）的316L不銹鋼，降低微生物黏附概率。</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">2. 運(yùn)行階段的動(dòng)態(tài)監(jiān)控體系</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">（1）微生物預(yù)警機(jī)制</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 在線ATP熒光儀實(shí)時(shí)監(jiān)測(cè)（閾值設(shè)定50RLU），超標(biāo)時(shí)自動(dòng)觸發(fā)預(yù)沖洗程序；</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 每月對(duì)膜進(jìn)水端、產(chǎn)水端進(jìn)行微生物鑒定（16S rRNA測(cè)序），建立優(yōu)勢(shì)菌庫(kù)，針對(duì)性調(diào)整消毒策略。</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">（2）數(shù)據(jù)完整性管理</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 清洗記錄需包含：時(shí)間、藥劑濃度、溫度、壓力、檢測(cè)結(jié)果（如電導(dǎo)率、TOC、微生物計(jì)數(shù)），保存期≥5年；</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 采用電子數(shù)據(jù)管理系統(tǒng)（EDMS），實(shí)現(xiàn)清洗流程的自動(dòng)追溯與趨勢(shì)分析（如壓差波動(dòng)標(biāo)準(zhǔn)差≤0.05MPa，內(nèi)部標(biāo)準(zhǔn)為主）。</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">3. 驗(yàn)證與合規(guī)要點(diǎn)</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">（1）清潔驗(yàn)證三大核心</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 有效性：連續(xù)3次清洗后，膜元件微生物負(fù)載≤10CFU/100cm2，內(nèi)毒素≤0.01EU/mL；</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 重現(xiàn)性：同一污染程度下，清洗后產(chǎn)水量恢復(fù)率≥90%，脫鹽率≥99.5%；</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 安全性：清洗劑殘留檢測(cè)（如次氯酸鈉≤0.1ppm，過(guò)氧乙酸≤0.5ppm），符合《中國(guó)藥典》通則要求。</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">（2）2025 GMP新增驗(yàn)證項(xiàng)目</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 生物膜挑戰(zhàn)測(cè)試：人為接種嗜熱脂肪芽孢桿菌孢子（10^6CFU/cm2），驗(yàn)證清洗工藝的滅活能力（Log reduction≥6）；</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;">- 消毒周期再確認(rèn)：根據(jù)季節(jié)變化（夏季微生物繁殖快），將RO膜消毒頻率從每月1次調(diào)整為每2周1次。</p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section><section style="justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: bottom; width: auto; line-height: 0; align-self: flex-end; flex: 0 0 0%; height: auto; box-sizing: border-box;"><section style=" transform: translate3d(-5px, 0px, 0px); -webkit-transform: translate3d(-5px, 0px, 0px); -moz-transform: translate3d(-5px, 0px, 0px); -o-transform: translate3d(-5px, 0px, 0px); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 9px; height: 9px; vertical-align: top; overflow: hidden; border-radius: 100px; background-color: rgb(195, 224, 247); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section><section style="display: inline-block; vertical-align: bottom; width: auto; flex: 100 100 0%; height: auto; align-self: flex-end; padding: 0px; box-sizing: border-box;"><section style="color: rgb(195, 224, 247); box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Oxytech<br style="box-sizing: border-box;"/></strong></p></section><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style=" transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); text-align: center; margin: 0px 0px 3px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section></section></section></section></section><section style="color: rgb(62, 62, 62); text-align: center; justify-content: center; display: flex; flex-flow: row; margin: 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: auto; vertical-align: top; align-self: flex-start; flex: 100 100 0%; border-style: solid; border-width: 0px 0px 0px 1px; border-color: rgb(195, 224, 247); height: auto; margin: 0px 0px 0px 4px; box-sizing: border-box;"><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; padding: 0px 27px; box-sizing: border-box;"><section style="text-align: justify; font-size: 17px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 24px; box-sizing: border-box;"><strong style="box-sizing: border-box;">應(yīng)急處理與消毒策略</strong></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"> </span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">1. 高效消毒劑選擇</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"> </span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 奧克泰士殺孢子劑：<span style="color: rgb(255, 129, 36); box-sizing: border-box;"><strong style="box-sizing: border-box;">復(fù)合成分高效協(xié)同作用雙重輔助滅菌，可殺滅包括芽孢在內(nèi)的所有微生物，無(wú)殘留且對(duì)設(shè)備高度友好基本無(wú)腐蝕。</strong></span>在完成日常清潔滅菌后，可作為終末滅菌處理，若添加到普清中，可作為交替消毒劑使用，作為末尾消毒劑適用確保滿足終滅條件。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">2. 消毒方案設(shè)計(jì)</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;">- 常規(guī)消毒：每固定時(shí)間采用巴氏消毒法擦拭臺(tái)面，每階段性時(shí)間采用<strong style="box-sizing: border-box;">奧克泰士消毒劑</strong>進(jìn)行循環(huán)沖洗消毒滅菌處理！</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: bottom; width: auto; line-height: 0; align-self: flex-end; flex: 0 0 0%; height: auto; box-sizing: border-box;"><section style=" transform: translate3d(-5px, 0px, 0px); -webkit-transform: translate3d(-5px, 0px, 0px); -moz-transform: translate3d(-5px, 0px, 0px); -o-transform: translate3d(-5px, 0px, 0px); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 9px; height: 9px; vertical-align: top; overflow: hidden; border-radius: 100px; background-color: rgb(195, 224, 247); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section><section style="display: inline-block; vertical-align: bottom; width: auto; flex: 100 100 0%; height: auto; align-self: flex-end; padding: 0px; box-sizing: border-box;"><section style="color: rgb(195, 224, 247); box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">Oxytech<br style="box-sizing: border-box;"/></strong></p></section><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style=" transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); text-align: center; margin: 0px 0px 3px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section></section></section></section></section><p style="color: rgb(62, 62, 62); margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p><section style="color: rgb(62, 62, 62); text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: top; width: auto; background-color: rgb(149, 185, 238); min-width: 5%; max-width: 100%; flex: 0 0 auto; height: auto; padding: 0px 10px; box-sizing: border-box;"><section style="text-align: center; margin: 6px 0px 0px; position: static; box-sizing: border-box;"><section style="color: rgb(255, 255, 255); font-size: 20px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;">四、消毒劑適用處理</strong></p></section></section></section><section style="display: inline-block; vertical-align: top; width: auto; margin: 0px 0px 0px -1px; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="position: static; transform: perspective(0px); -webkit-transform: perspective(0px); -moz-transform: perspective(0px); -o-transform: perspective(0px); transform-style: flat; box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; transform: rotateY(180deg); -webkit-transform: rotateY(180deg); -moz-transform: rotateY(180deg); -o-transform: rotateY(180deg); position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; background-image: linear-gradient(90deg, rgba(235, 246, 255, 0) 0%, rgb(235, 246, 255) 80%); box-sizing: border-box;"><section style="justify-content: flex-start; display: flex; flex-flow: row; position: static; box-sizing: border-box;"><section style="display: inline-block; vertical-align: middle; width: auto; align-self: center; flex: 100 100 0%; height: auto; box-sizing: border-box;"><section style="margin: 0.5em 0px; position: static; box-sizing: border-box;"><section style="background-image: linear-gradient(90deg, rgba(149, 197, 238, 0) 13%, rgb(149, 197, 238) 88%); height: 1px; box-sizing: border-box;"><svg viewbox="0 0 1 1" style="float:left;line-height:0;width:0;vertical-align:top;"></svg></section></section></section><section style="display: inline-block; vertical-align: middle; width: auto; flex: 0 0 0%; height: auto; align-self: center; box-sizing: border-box;"><section style="text-align: right; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 0px; height: 0px; vertical-align: top; overflow: hidden; border-style: solid; border-width: 19px 12px 19px 0px; border-color: rgba(255, 255, 255, 0) rgb(149, 185, 238) rgba(255, 255, 255, 0) rgba(255, 255, 255, 0); box-sizing: border-box;"><section style="text-align: justify; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><br style="box-sizing: border-box;"/></p></section></section></section></section></section></section></section></section></section></section><section style="text-align: center; justify-content: center; display: flex; flex-flow: row; margin: 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: auto; vertical-align: top; align-self: flex-start; flex: 100 100 0%; border-style: solid; border-width: 0px 0px 0px 1px; border-color: rgb(195, 224, 247); height: auto; margin: 0px 0px 0px 4px; box-sizing: border-box;"><section style="text-align: left; justify-content: flex-start; display: flex; flex-flow: row; margin: 10px 0px 0px; position: static; box-sizing: border-box;"><section style="display: inline-block; width: 100%; vertical-align: top; align-self: flex-start; flex: 0 0 auto; padding: 0px 27px; box-sizing: border-box;"><section style="color: rgb(62, 62, 62); text-align: justify; font-size: 17px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><span style="font-size: 18px; box-sizing: border-box;"><strong style="box-sizing: border-box;">我們要如何處理降低風(fēng)險(xiǎn)：</strong></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; box-sizing: border-box;"><strong style="box-sizing: border-box;"><br style="box-sizing: border-box;"/></strong></p></section><section style="color: rgb(62, 62, 62); text-align: justify; font-size: 17px; box-sizing: border-box;"><p style="margin-top: 0px; margin-bottom: 0px; 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